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The Patterns of Ablaut Reduplication in Toba Batak: A Construction-Based Approach
REiLA : Journal of Research and Innovation in Language; Vol. 7 No. 1 (2025): REiLA : Journal of Research and Innovation in Language; 29-44
The study addresses a critical gap in morphological research by investigating the understudied patterns of ablaut reduplication in Toba Batak (TB), an endangered Austronesian language, through a construction-based approach. While ablaut reduplication...
PubMed
Interphase cohesin regulation ensures mitotic fidelity after genome reduplication
Mol Biol Cell
To ensure faithful genome propagation, mitotic cells alternate one round of chromosome duplication with one round of chromosome separation. Chromosome separation failure thus causes genome reduplication, which alters mitotic chromosome structure. Suc...
PubMed
Cyclin A2-Cyclin-Dependent Kinase 2 Cooperates with the PLK1-SCF(β-TrCP1)-EMI1-Anaphase-Promoting Complex/Cyclosome Axis To Promote Genome Reduplication in the Absence of Mitosis
Mol Cell Biol
Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Inhibition of cyclin-dependent kinase 1 (CDK1) with the specific inhibitor RO3306 is sufficient to trigger multiple rounds of genome reduplication. We demon...
PubMed
Aspectual reduplication in Sign Language of the Netherlands: reconsidering phonological constraints and aspectual distinctions
Linguistics
This study investigates the use of predicate reduplication to express aspectual meaning in Sign Language of the Netherlands (NGT). The study focuses on three aspect types that have been found to be encoded by reduplication across sign languages – ...
PubMed
Productive reduplication in a fundamentally monosyllabic language
Lang Sci
The question to be addressed in this paper is how a language which is fundamentally monosyllabic in structure can have about a dozen different reduplication types with at least eight different linguistic functions. The language under discussion, Amer...
PubMed
Preventing the Degradation of Mps1 at Centrosomes Is Sufficient to Cause Centrosome Reduplication in Human Cells
Mol Biol Cell
Supernumerary centrosomes promote the assembly of abnormal mitotic spindles in many human tumors. In human cells, overexpression of the cyclin-dependent kinase (Cdk)2 partner cyclin A during a prolonged S phase produces extra centrosomes, called cent...
PubMed
Centriole reduplication during prolonged interphase requires procentriole maturation governed by Plk1
Curr Biol
Supernumerary centrioles lead to abnormal mitosis [1,2] which in turn promotes tumorigenesis [3,4]. Thus, centriole duplication must be coordinated with the cell cycle to ensure that the number of centrioles in the cell doubles precisely during each ...
PubMed
Intrinsic and Cyclin-dependent Kinase-dependent Control of Spindle Pole Body Duplication in Budding Yeast
Mol Biol Cell
Centrosome duplication must be tightly controlled so that duplication occurs only once each cell cycle. Accumulation of multiple centrosomes can result in the assembly of a multipolar spindle and lead to chromosome mis-segregation and genomic instabi...
PubMed
Environmental reduplication associated with right frontal and parietal lobe injury.
J Neurol Neurosurg Psychiatry
Four patients with environmental reduplication, a specific form of spatial disorientation and confabulation are described. The patients maintained that their hospital rooms were located in their homes. Each patients had evidence of right frontal or r...
PubMed
Abstract representations in temporal cortex support generative linguistic processing
Lang Cogn Neurosci
Generativity, the ability to create and evaluate novel constructions, is a fundamental property of human language and cognition. The productivity of generative processes is determined by the scope of the representations they engage. Here we examine t...
PubMed
The SCF(Slimb) ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication
J Cell Biol
Restricting centriole duplication to once per cell cycle is critical for chromosome segregation and genomic stability, but the mechanisms underlying this block to reduplication are unclear. Genetic analyses have suggested an involvement for Skp/Culli...
PubMed
The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication
J Cell Sci
Centrosomes are the major microtubule-organizing centers in animal cells and regulate formation of a bipolar mitotic spindle. Aberrant centrosome number causes chromosome mis-segregation, and has been implicated in genomic instability and tumor devel...
PubMed
Processing Mandarin Tone 3 Sandhi at the Morphosyntactic Interface: Reduplication and Lexical Compounds
Front Psychol
Mandarin tone 3 sandhi is a phonological alternation in which the initial tone 3 (i.e., low tone) syllable changes to a tone 2 (i.e., rising tone) when followed by another tone 3. The present study used a cross-modal syllable-morpheme matching experi...
PubMed
Serum osteocalcin levels are inversely associated with plasma glucose and body mass index in healthy Chinese women
Acta Pharmacol Sin
AIM: Osteocalcin, a biochemical marker of bone formation, has been suggested to be involved in the regulation of energy metabolism. The aim of this study was to investigate the possible association between serum osteocalcin and markers of glucose and...
PubMed
Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation
Nat Commun
Centrosome overduplication promotes mitotic abnormalities, invasion and tumorigenesis. Cells regulate the number of centrosomes by limiting centriole duplication to once per cell cycle. The orthogonal orientation between a mother and a daughter centr...
PubMed
The putative promoter of a Xenopus laevis ribosomal gene is reduplicated.
Nucleic Acids Res
With the aid of a novel poly-dA tailing-partial restriction technique and S1-protection mapping, the 5' terminal coding sequence for the 40S precursor ribosomal RNA of Xenopus laevis has been exactly identified. Since the promoter sequence for t...
PubMed
Cyclin E in Centrosome Duplication and Reduplication in Sea Urchin Zygotes
J Cell Physiol
When protein synthesis is completely blocked from before fertilization, the sea urchin zygote arrests in first S phase and the paternal centrosome reduplicates multiple times. However, when protein synthesis is blocked starting in prophase of first m...
PubMed
Why Choo‐Choo Is Better Than Train: The Role of Register‐Specific Words in Early Vocabulary Growth
Cogn Sci
Across languages, lexical items specific to infant‐directed speech (i.e., ‘baby‐talk words’) are characterized by a preponderance of onomatopoeia (or highly iconic words), diminutives, and reduplication. These lexical characteristics may help...
PubMed
Distinct responses to reduplicated chromosomes require distinct Mad2 responses
eLife
Duplicating chromosomes once each cell cycle produces sister chromatid pairs, which separate accurately at anaphase. In contrast, reduplicating chromosomes without separation frequently produces polytene chromosomes, a barrier to accurate mitosis. Ch...
PubMed
Learning multiple rules simultaneously: Affixes are more salient than reduplications
Mem Cognit
Language learners encounter numerous opportunities to learn regularities, but need to decide which of these regularities to learn, because some are not productive in their native language. Here, we present an account of rule learning based on percept...