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Repositori Institusi
LIMAS edisi Nomor 35 November 2016
Materi tulisan pada edisi kali ini antara lain mengenai implementasi kurikulum 2013, pentingnya kemampuan mengomunikasikan gagasan bagi guru matematika, koneksi matematis, serta integrasi pendidikan etika berlalu lintas (ELL) pada mata pelajaran mate...
Jurnal Institusi
First Language Interfere in EFL Classes: Revealing Students’ Perspectives and Teachers’ Reasons in ELL:
REiLA : Journal of Research and Innovation in Language; Vol. 5 No. 1 (2023): REiLA : Journal of Research and Innovation in Language ; 77-88
Multilingualism is a common phenomenon among Indonesian students who are proficient in both national and local languages. However, the use of the first language (L1) in English as a Foreign Language (EFL) classrooms has been a subject of ongoing deba...
Jurnal Institusi
Midwifery Students' Perceptions of Utilizing Artificial Intelligence (AI) for English Language Learning (ELL)
Elsya : Journal of English Language Studies; Vol. 7 No. 1 (2025): Elsya : Journal of English Language Studies ; 90-100
This study aims to explore the language politeness of elementary school students in daily interactions, analyze the integration of digital literacy in Indonesian language learning, and describe the barriers in the process. Using a qualitative approac...
PubMed
Molecular Basis of p53 Functional Inactivation by the Leukemic Protein MLL-ELL
Mol Cell Biol
The Eleven Lysine-rich Leukemia (ELL) gene undergoes translocation and fuses in frame to the Multiple Lineage Leukemia (MLL) gene in a substantial proportion of patients suffering from acute forms of leukemia. Molecular mechanisms of cellular transfo...
PubMed
ELL Inhibits E2F1 Transcriptional Activity by Enhancing E2F1 Deacetylation via Recruitment of Histone Deacetylase 1
Mol Cell Biol
ELL (eleven-nineteen lysine-rich leukemia protein) was first identified as a translocation partner of MLL in acute myeloid leukemia; however, the exact mechanism of its action has remained elusive. In this study, we identified ELL as a direct downstr...
PubMed
ELL and EAF1 are Cajal Body Components That Are Disrupted in MLL-ELL Leukemia
Mol Biol Cell
The (11;19)(q23;p13.1) translocation in acute leukemia results in the formation of a chimeric MLL-ELL fusion protein. ELL is an RNA Polymerase II (Pol II) transcriptional elongation factor that interacts with the recently identified EAF1 protein. Her...
PubMed
ELL is an HIF-1α partner that regulates and responds to hypoxia response in PC3 cells
Prostate
BACKGROUND: ELL plays an important role in tumorigenesis and animal development. HIF-1 is a transcriptional factor that functions as a master regulator of O(2) homeostasis. Our previous studies showed that a binding partner of ELL, U19/Eaf2, can modu...
PubMed
Functional Analysis of the Leukemia Protein ELL: Evidence for a Role in the Regulation of Cell Growth and Survival
Mol Cell Biol
The ELL gene encodes an RNA polymerase II transcription factor that frequently undergoes translocation with the MLL gene in acute human myeloid leukemia. Here, we report that ELL can regulate cell proliferation and survival. In order to better unders...
PubMed
The Elongation Domain of ELL Is Dispensable but Its ELL-Associated Factor 1 Interaction Domain Is Essential for MLL-ELL-Induced Leukemogenesis
Mol Cell Biol
The MLL-ELL chimeric gene is the product of the (11;19)(q23p13.1) translocation associated with de novo and therapy-related acute myeloid leukemias (AML). ELL is an RNA polymerase II elongation factor that interacts with the recently identified EAF1 ...
PubMed
Elongation Factor ELL (Eleven-Nineteen Lysine-rich Leukemia) Acts as a Transcription Factor for Direct Thrombospondin-1 Regulation
J Biol Chem
The eleven-nineteen lysine-rich leukemia (ELL) gene undergoes translocation and fuses in-frame to the multiple lineage leukemia gene in a substantial proportion of patients suffering from acute forms of leukemia. Studies show that ELL indirectly modu...
PubMed
Developmental analysis and subcellular localization of the murine homologue of ELL
Proc Natl Acad Sci U S A
The ELL gene was first identified by its involvement with MLL in the translocation (11;19)(q23;p13.1) in acute myeloid leukemia. To date, nine other MLL partner genes have been cloned, but their precise functions have yet to be determined. To charact...
PubMed
Resilience and traumatic stress among Latinx english language learners: a cross-sectional study of students from an urban school district
BMC Public Health
BACKGROUND: Latinx students in the United States can face stressors and structural inequities that can lead to poor academic and mental health outcomes. They comprise 76% of the English Language Learner (ELL) population, yet little is known about the...
PubMed
EXAMINING THE EFFECTOF LANGUAGE-BASED INSTRUCTIONAL INTERVENTIONS ON ELL AND NON-ELL LANGUAGE PRODUCTION AND TASK-ORIENTED BEHAVIOR IN ELEMENTARY MATH, SCIENCE, AND SOCIAL STUDIES CLASSROOMS
J Teach Action Res
As the population of K–12 English language learners (ELLs) grows, teachers are challenged to employ strategies that efficiently promote content-learning and language-learning. This paper reports an action research project investigating the effects ...
PubMed
Negative Feedback Loop Mechanism between EAF1/2 and DBC1 in Regulating ELL Stability and Functions
Mol Cell Biol
Although ELL-associated factors 1 and 2 (EAF1/2) have been shown to enhance RNA polymerase II-mediated transcription in vitro, their functional roles in vivo are poorly known. In this report, we show functions of these proteins in regulating ELL stab...
PubMed
Appropriateness of laboratory expenditure for primary health care facilities across South Africa
Afr J Prim Health Care Fam Med
BACKGROUND: Primary health care (PHC) services have been prioritised from a cost-containment perspective. To manage expenditure, facility managers use the Laboratory Handbook that indicates the Essential Laboratory List (ELL) tests. AIM: The aim of t...
PubMed
ELL2, a new member of an ELL family of RNA polymerase II elongation factors
Proc Natl Acad Sci U S A
We recently isolated an RNA polymerase II elongation factor from rat liver nuclei and found it to be homologous to the product of the human ELL gene, a frequent target for translocations in acute myeloid leukemia. To further our understanding of the ...
PubMed
DBC1, p300, HDAC3, and Siah1 coordinately regulate ELL stability and function for expression of its target genes
Proc Natl Acad Sci U S A
Among all of the Super Elongation Complex (SEC) components, ELL1 (also known as ELL) is the only bona fide elongation factor that directly stimulates transcription elongation by RNA polymerase II. However, the mechanism(s) of functional regulation of...
PubMed
ELL targets c-Myc for proteasomal degradation and suppresses tumour growth
Nat Commun
Increasing evidence supports that ELL (eleven–nineteen lysine-rich leukaemia) is a key regulator of transcriptional elongation, but the physiological function of Ell in mammals remains elusive. Here we show that ELL functions as an E3 ubiquitin lig...
PubMed
Supporting Children Who Are English Language Learners Succeed in Their Early Literacy Development
Folia Phoniatr Logop
INTRODUCTION: The Better Start Literacy Approach is an example of a multi-tiered system of support (MTSS) to facilitate children's early literacy success. It is set within a strengths-based and culturally responsive framework for literacy teachi...
PubMed
ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL
Proc Natl Acad Sci U S A
In human cells, the ELL family of transcription factors includes at least three members, which are all capable of stimulating the overall rate of elongation by RNA polymerase II by suppressing transient pausing by the enzyme at many sites along DNA. ...