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Jurnal Institusi
UJI SITOTOKSIK TUMBUHAN OBAT DI HUTAN ADAT SINAGA SUMATERA UTARA
Wahana Forestra: Jurnal Kehutanan; Vol. 17 No. 1 (2022); 69-84
Toxicity test can be conduct using Artemia salina shrimp larvae. For this reason do a research aimed to identifying 5 types of medicinal plants, and assessing the bioactivity content of five types of anticancer medicinal plants as cytotoxic...
Jurnal Institusi
Properties and Toxicity of Cobalt(II) Complex with 2,4,5-triphenyl-1H-imidazole Ligand
Indonesian Journal of Chemistry; Vol 16, No 3 (2016); 260-267
Binuclear cobalt(II) complex with 2,4,5-triphenyl-1H-imidazole ligand has been synthesized using reflux method. The yellowish green crystals with needle-like shape were obtained. Determination of molecular formula of the complex was carried out using...
PubMed
Use of the TIPS Technique as a Possible Method of Acute Inhalation Toxicity Assessment
J Appl Toxicol
Acute inhalation toxicity studies provide crucial information regarding short‐term exposure to volatile chemicals and help to ensure the safe handling and use of these chemicals. However, acute inhalation toxicity assessment requires specialized eq...
PubMed
Commercial formulations of Bacillus thuringiensis for control of Indian meal moth.
Appl Environ Microbiol
Doses of four commercial formulations and one experimental formulation of Bacillus thuringiensis Berliner were mixed with the diet used to rear colonies of the Indian meal moth Plodia interpunctella (Hübner). Indian meal moth eggs were introduced to...
PubMed
Electrophiles and acute toxicity to fish.
Environ Health Perspect
Effect concentrations in fish LC50 tests with directly acting electrophiles are lower than those of unreactive chemicals that act by narcosis. LC50 values of more hydrophobic reactive chemicals tend to approach those of unreactive chemicals. Quantita...
PubMed
Insecticidal activities of Citrus aurantifolia essential oil against Aedes aegypti (Diptera: Culicidae)
Toxicol Rep
BACKGROUND: In the recent time, global attention for the control of vectors has shifted from chemical insecticides to botanicals. In the present investigation, authors attempted to evaluate the efficacy of peel and leaf essential oil (EO) of Citrus a...
PubMed
Cytotoxicity and Antioxidant Activity of 23 Plant Species of Leguminosae Family
Iran J Pharm Res
Numerous studies have been focused on natural anticarcinogenic agents. Many antioxidants have been identified as anticarcinogens. Antimutagens have also been proposed as cancer chemopreventive agents. The use of natural products as anticancer has a l...
PubMed
Heterogeneity and Plasticity of Human Breast Cancer Cells in Response to Molecularly-Targeted Drugs
Front Oncol
Non-responsive subpopulation of tumor cells, and acquired resistance in initially responsive cells are major challenges for cancer therapy with molecularly-targeted drugs. While point mutations are considered the major contributing factor to acquired...
PubMed
Persistent susceptibility of Aedes aegypti to eugenol
Sci Rep
Botanical insecticides are preferred for their environment and user-friendly nature. Eugenol is a plant-based monoterpene having multifarious biocidal activities. To understand whether eugenol would persistently work against Aedes aegypti, we perform...
PubMed
The Biocompatibility of a New Erythritol-and Xyltol-Containing Fluoride Toothpaste
Healthcare (Basel)
The basic function of toothpastes is biofilm removal in order to prevent caries and gingivitis. Toothpastes should provide maximal fluoride availability, optimal abrasivity, and ingredients that do not interfere with fluoride release but should have ...
PubMed
Toxicological effect and enzymatic disorder of non-studied emerging contaminants in Artemia salina model
Toxicol Rep
Emerging contaminants such as sunscreens, hair dyes and flame retardants have been found at important concentrations in surface water (river, lake, ocean), but their negative impact on different aquatic species is not fully known. This study evaluate...
PubMed
Acaricidal efficacy of fluralaner against Rhipicephalus microplus ticks under laboratory and field conditions in Brazil
Parasit Vectors
BACKGROUND: The first isoxazoline-based acaricide (fluralaner) for the control of Rhipicephalus microplus was introduced onto the market in 2022, initially in Brazil, followed by other Latin American countries. Therefore, it is important to establish...
PubMed
Toxicity of parasporal crystals of Bacillus thuringiensis subsp. israelensis to mosquitoes.
Appl Environ Microbiol
Toxicity of Bacillus thuringiensis subsp. israelensis (ONR-60A/WHO 1897) parasporal crystals to three medically important mosquito larvae is described. The numbers of larvae killed are in relation to crystal dry weight. The crystals are lethally toxi...
PubMed
Basophil sensitivity through CD63 or CD203c is a functional measure for specific immunotherapy
Clin Mol Allergy
BACKGROUND: Subcutaneous Immunotherapy (SCIT) modifies the allergic response and relieves allergic symptoms. SCIT is the only and a very effective treatment for insect venom allergy. We hypothesized that basophil sensitivity, measured through the bas...
PubMed
Combined effects of ammonia-N exposure and salinity changes on hematological and serum biochemical factors and thyroid hormones in Nile tilapia (Oreochromis niloticus)
Heliyon
The aim of this research was to evaluate the interaction effects of ammonia-N levels and salinity on hematological and serum biochemical parameters in Nile tilapia (Oreochromis niloticus). The fish were randomly divided into 12 treatments including t...
PubMed
The Potential for Salt Toxicity: Can the Trans-Epithelial Potential (TEP) Across the Gills Serve as a Metric for Major Ion Toxicity in Fish?
Aquat Toxicol
An emerging Multi-Ion Toxicity (MIT) model for assessment of environmental salt pollution is based on the premise that major ion toxicity to aquatic organisms is related to a critical disturbance of the trans-epithelial potential across the gills (Δ...
PubMed
Concentration-time interactions in hydrogen sulphide toxicity in rats.
Can J Vet Res
Concentration-time interactions were investigated in young male and female Sprague-Dawley, Long Evans and Fischer-344 rats exposed to hydrogen sulphide for two, four or six hours. Higher concentrations caused more deaths, with no significant differen...
PubMed
Toxicity of cigarette butts, and their chemical components, to marine and freshwater fish
Tob Control
BACKGROUND: Cigarette butts are the most common form of litter, as an estimated 4.5 trillion cigarette butts are thrown away every year worldwide. Many chemical products are used during the course of growing tobacco and manufacturing cigarettes, the ...
PubMed
Toxicity, uptake, and mutagenicity of particulate and soluble nickel compounds.
Environ Health Perspect
Toxicity testing in AS52 cells (24-hr exposures) gave LC50 values of 2 to 130 micrograms Ni/ml for particulate nickel compounds and 45 to 60 micrograms Ni/ml for water-soluble salts (NiCl2, NiSO4, Ni(CH3COO)2). The Ni(OH)2, NiCO3, and sulfides (Ni3S2...
PubMed
A comparison of electronic and traditional cigarette butt leachate on the development of Xenopus laevis embryos
Toxicol Rep
Potential developmental toxicities of three different cigarette butt leachates were evaluated using the frog embryo teratogenesis assay–Xenopus (FETAX). Xenopus laevis embryos were exposed to regular cigarette butt (RCB), menthol (MCB) and electron...