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# Judul Penulis Tahun Akses
Jurnal Institusi

Comparison of NAA XRF and ICP-OES Methods on Analysis of Heavy Metals in Coals and Combustion Residues

Indonesian Journal of Chemistry; Vol 17, No 2 (2017); 228-237
Universitas Gadjah Mada, 2017DOI: 10.22146/ijc.17686http://creativecommons.org/licenses/by-nc-nd/4.0
Heavy metals in the samples of coals and combustion residues (bottom ash and fly ash) from Pacitan coal-fired power plant (CPP) have been identified by using NAA, XRF, and ICP-OES methods. This research was aimed to understand the analysis results co...
PubMed

Nucleic acid amplification tests reduce delayed diagnosis and misdiagnosis of pulmonary tuberculosis

Sci Rep
Nature Publishing Group, 2022DOI: 10.1038/s41598-022-16319-8https://creativecommons.org/licenses/by/4.0/
The clinical impact of nucleic acid amplification (NAA) tests on reducing delayed diagnosis and misdiagnosis of pulmonary TB (PTB) has rarely been investigated. PTB patients were classified into a frontline NAA group, an add-on NAA group, and a no NA...
PubMed

N-Acetylaspartate Metabolism Outside the Brain: Lipogenesis, Histone Acetylation, and Cancer

Front Endocrinol (Lausanne)
Frontiers Media SA, 2017DOI: 10.3389/fendo.2017.00240https://creativecommons.org/licenses/by/4.0/
N-acetylaspartate (NAA) is a highly abundant brain metabolite. Aberrant NAA concentrations have been detected in many pathological conditions and although the function of NAA has been extensively investigated in the brain it is still controversial. O...
PubMed

Circulating N-Acetylaspartate does not track brain NAA concentrations, cognitive function or features of small vessel disease in humans

Sci Rep
Nature Publishing Group, 2022DOI: 10.1038/s41598-022-15670-0https://creativecommons.org/licenses/by/4.0/
N-acetylaspartate (NAA) is the second most abundant metabolite in the human brain; although it is assumed to be a proxy for a neuronal marker, its function is not fully elucidated. NAA is also detectable in plasma, but its relation to cerebral NAA le...
PubMed

Ovarian Cyst Fluid of Serous Ovarian Tumors Contains Large Quantities of the Brain Amino Acid N-acetylaspartate

PLoS One
PLOS, 2010DOI: 10.1371/journal.pone.0010293https://creativecommons.org/licenses/by/4.0/
BACKGROUND: In humans, N-acetyl L-aspartate (NAA) has not been detected in other tissues than the brain. The physiological function of NAA is yet undefined. Recently, it has been suggested that NAA may function as a molecular water pump, responsible ...
PubMed

Hippocampal region metabolites and cognitive impairment in patients with general paresis: based on (1)H-proton magnetic resonance spectroscopy

Front Pharmacol
Frontiers Media SA, 2024DOI: 10.3389/fphar.2024.1382381https://creativecommons.org/licenses/by/4.0/
BACKGROUND: This study utilizes Hydrogen proton magnetic resonance spectroscopy ((1)H-MRS) to investigate metabolite concentrations in the bilateral hippocampus of general paresis (GP) patients. METHODS: A total of 80 GP patients and 57 normal contr...
PubMed

Mechanism of Naphthaleneacetic Acid Conjugation

Plant Physiol
Oxford University Press, 1973DOI: 10.1104/pp.51.5.907
Formation of naphthaleneacetic acid-glucose (NAGLu) in detached leaves, floating on α-naphthaleneacetic acid-1-(14)C (NAA, 0.05 microcurie per milliliter, 3.1 μm)-buffer solution (phosphate-citrate, pH 4.2) began immediately while there was a 2- to...
PubMed

Disarrangement of Fiber Tracts and Decline of Neuronal Density Correlate in Glioma Patients—A Combined Diffusion Tensor Imaging and (1)H-MR Spectroscopy Study

AJNR Am J Neuroradiol
American Society of Neuroradiology, 2006Copyright © American Society of Neuroradiology
BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) and MR spectroscopy are noninvasive, quantitative tools for the preoperative assessment of gliomas with which the quantitative parameter fractional anisotropy (FA) and the concentration of neurom...
PubMed

N-Acetylaspartate Synthase Deficiency Corrects the Myelin Phenotype in a Canavan Disease Mouse Model But Does Not Affect Survival Time

J Neurosci
Society for Neuroscience, 2015DOI: 10.1523/JNEUROSCI.1056-15.2015Copyright © 2015 the authors 0270-6474/15/3514501-16$15.00/0
Canavan disease (CD) is a severe, lethal leukodystrophy caused by deficiency in aspartoacylase (ASPA), which hydrolyzes N-acetylaspartate (NAA). In the brains of CD patients, NAA accumulates to high millimolar concentrations. The pathology of the dis...
PubMed

Use of Nucleic Acid Amplification Testing for Rapid Detection of Mycobacterium tuberculosis Complex Among US Tuberculosis Patients, 2011‒2017

Open Forum Infect Dis
Oxford University Press, 2021DOI: 10.1093/ofid/ofab528Published by Oxford University Press on behalf of Infectious Diseases Society of America 2021. This work is written by (a) US Government employee(s) and is in the public domain in the US.
BACKGROUND: Nucleic acid amplification (NAA) tests rapidly detect Mycobacterium tuberculosis complex directly from clinical specimens, providing valuable results for those evaluated for tuberculosis. METHODS: We analyzed characteristics of cases with...
PubMed

Targeted Sodium Acetate Liposomes for Hepatocytes and Kupffer Cells: An Oral Dual-Targeted Therapeutic Approach for Non-Alcoholic Fatty Liver Disease Alleviation

Nutrients
Multidisciplinary Digital Publishing Institute (MDPI), 2025DOI: 10.3390/nu17050930https://creativecommons.org/licenses/by/4.0/
Background/Objectives: Sodium acetate (NaA) has demonstrated potential in improving non-alcoholic fatty liver disease (NAFLD) by targeting hepatocytes and Kupffer cells. However, its clinical application is hindered by low oral bioavailability and in...
PubMed

Dynamic or inert metabolism? Turnover of N-acetyl aspartate and glutathione from D-[1-(13)C]glucose in the rat brain in vivo

J Neurochem
The rate of (13)C-label incorporation into both aspartyl (NAA C3) and acetyl (NAA C6) groups of N-acetyl aspartate (NAA) was simultaneously measured in the rat brain in vivo for up to 19 h of [1-(13)C]glucose infusion (n = 8). Label incorporation was...
PubMed

Value of single-voxel proton MR spectroscopy in temporal lobe epilepsy.

AJNR Am J Neuroradiol
American Society of Neuroradiology, 1997Copyright © American Society of Neuroradiology
PURPOSE: To study the value of different parameters derived from single-voxel proton MR spectroscopy of the mesial temporal lobes in the lateralization of the epileptogenic zone in patients with temporal lobe epilepsy. METHODS: We studied 12 healthy ...
PubMed

Association between Proton Magnetic Resonance Spectroscopy Measurements and CAG Repeat Number in Patients with Spinocerebellar Ataxias 2, 3, or 6

PLoS One
PLOS, 2012DOI: 10.1371/journal.pone.0047479https://creativecommons.org/licenses/by/4.0/
The aim of this study was to correlate magnetic resonance spectroscopy (MRS) measurements, including that for the N-acetyl aspartate (NAA)/creatine (Cr) ratio in the vermis (denoted V-NAA), right cerebellar hemisphere (R-NAA), and left (L-NAA) cerebe...
PubMed

Bidirectional Regulation of Sodium Acetate on Macrophage Activity and Its Role in Lipid Metabolism of Hepatocytes

Int J Mol Sci
Multidisciplinary Digital Publishing Institute (MDPI), 2023DOI: 10.3390/ijms24065536https://creativecommons.org/licenses/by/4.0/
Short-chain fatty acids (SCFAs) are important metabolites of the intestinal flora that are closely related to the development of non-alcoholic fatty liver disease (NAFLD). Moreover, studies have shown that macrophages have an important role in the pr...
PubMed

N-Acetylaspartate Is an Important Brain Osmolyte

Biomolecules
Multidisciplinary Digital Publishing Institute (MDPI), 2020DOI: 10.3390/biom10020286http://creativecommons.org/licenses/by/4.0/
Most of the human diseases related to various proteopathies are confined to the brain, which leads to the development of various forms of neurological disorders. The human brain consists of several osmolytic compounds, such as N-Acetylaspartate (NAA)...
PubMed

N-acetylaspartate (NAA) correlates inversely with cannabis use in a frontal language processing region of neocortex in MDMA (Ecstasy) Polydrug Users: a 3 Tesla Magnetic Resonance Spectroscopy Study

Pharmacol Biochem Behav
Impaired verbal memory is common in MDMA (Ecstasy) polydrug users. The contributions of Ecstasy or polydrug exposure to reduced verbal memory are unclear, as is the neural basis for this cognitive deficit. Ecstasy users have reduced gray matter in br...
PubMed

TAMI-29. MR SPECTROSCOPY MEASURES OF LAC/NAA AND NAA/CHO DIFFERENTIATE SURVIVORSHIP IN PATIENTS WITH RECURRENT GLIOBLASTOMA TREATED WITH ANTI-ANGIOGENIC THERAPY

Neuro Oncol
Oxford University Press, 2021DOI: 10.1093/neuonc/noab196.813© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)
Patients with recurrent glioblastoma (rGBM) are often started on anti-angiogenic therapy such as bevacizumab. However, determining treatment failure using conventional MRI methods remains challenging. We prospectively collected longitudinal MR spectr...
PubMed

Neuronal viability/astrocyte activity ratio in the dorsolateral prefrontal cortex as a biomarker of Alzheimer’s dementia: A proton magnetic resonance spectroscopy study

Alzheimers Dement
Wiley, 2025DOI: 10.1002/alz.090573https://creativecommons.org/licenses/by/4.0/
BACKGROUND: N‐acetyl‐aspartate (NAA) and myo‐inositol (mI) are neurometabolites reflecting neuronal viability and astrocyte activity, respectively. These can be quantified in vivo using proton magnetic resonance spectroscopy (1H‐MRS). Previou...
PubMed

Multi-Spectroscopic and Molecular Simulation Approaches to Characterize the Intercalation Binding of 1-Naphthaleneacetic Acid With Calf Thymus DNA

Front Toxicol
Frontiers Media SA, 2021DOI: 10.3389/ftox.2021.620501https://creativecommons.org/licenses/by/4.0/
1–Naphthaleneacetic acid (NAA), having high-quality biological activity and great yield-increasing potential in agricultural production, is a broad-spectrum plant growth regulator. Although NAA is of low toxicity, it can affect the balance of the h...