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Repositori Institusi
Technical study for rehabilitation on Prambanan Temple compound after earthquake
Prambanan temple complex as one of the world heritage site suffers damages after the earthquake. To rehabilitate the temples, some comprehensive technical studies which involve some disciplines are needed to carry out. This report is the compilation ...
Jurnal Institusi
Preservation of Natural Colorant Extract of Jalawe Fruit Peel (Terminalia bellirica) in Water-Based Solution
Indonesian Journal of Chemistry; Vol 16, No 3 (2016); 315-321
The general objective of this study is to preserve natural colorant extract of jalawe fruit peel in water-based solution during storing. The specific objectives in this research are finding suitable type and amount of antimicrobial compound to preven...
Jurnal Institusi
The Isolation of Xanthones from Trunk Latex of Garcinia mangostana Linn. and Their Antimicrobial Activities
Indonesian Journal of Chemistry; Vol 15, No 2 (2015); 187-193
ɑ-Mangostin (1), β-mangostin (2) and gartanin (3) have been isolated from the trunk latex of Garcinia mangostana Linn. and investigated for their antimicrobial activities against Bacillus subtilis, Enterococcus faecalis, Micrococcus luteus, Salmone...
Jurnal Institusi
Synthesis of ZnO Nanoparticles by Precipitation Method with Their Antibacterial Effect
Indonesian Journal of Chemistry; Vol 16, No 2 (2016); 117-123
The aim of this study was to synthesize and characterize Zinc oxide nanoparticles (ZnO-NPs) prepared by precipitation method. Zinc nitrate and sodium hydroxide was used as starting materials with biopolymer pectin as capping agent. ZnO-NPs were synth...
Jurnal Institusi
Potassium Permanganate-Catalyzed Alpha-Pinene Oxidation: Formation of Coordination Compound with Zinc(II) and Copper(II), and Growth Inhibition Activity on Staphylococcus aureus and Escherichia coli
Indonesian Journal of Chemistry; Vol 16, No 1 (2016); 59-64
Catalytic oxidation of alpha-pinene was investigated using potassium permanganate as an oxidant. The reaction consumed catalyst following stoichiometric amount instead of the catalytic one. The keto-carboxylate compound 2 was afforded as the oxidatio...
Jurnal Institusi
Two Isophalerin Compounds from Ethyl Acetate of Leave and Fruit of Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) and Its Antibacterial Activity
Indonesian Journal of Chemistry; Vol 15, No 2 (2015); 179-186
Mahkota dewa plant (Phaleria macrocarpa (Scheff.) Boerl.) which is belong to family of Thymelaeaceae is one of Indonesia's traditional medicines. The aim of this research is to isolate secondary metabolites from ethyl acetate extract of leave an...
Jurnal Institusi
The Phenolic Compound from Kalanchoe blossfeldiana (Crassulaceae) Leaf and Its Antiplasmodial Activity against Plasmodium falciparum 3D7
Indonesian Journal of Chemistry; Vol 16, No 2 (2016); 156-161
Various species of Kalanchoe plants have been widely used as raw materials in traditional medicines. This study was the continuation of the researches on secondary metabolites from Indonesia Kalanchoe plants, focused on Kalanchoe blossfeldiana. Fresh...
Jurnal Institusi
Properties and Toxicity of Cobalt(II) Complex with 2,4,5-triphenyl-1H-imidazole Ligand
Indonesian Journal of Chemistry; Vol 16, No 3 (2016); 260-267
Binuclear cobalt(II) complex with 2,4,5-triphenyl-1H-imidazole ligand has been synthesized using reflux method. The yellowish green crystals with needle-like shape were obtained. Determination of molecular formula of the complex was carried out using...
Jurnal Institusi
Methylation of Eugenol Using Dimethyl Carbonate and Bentonite as Catalyst
Indonesian Journal of Chemistry; Vol 15, No 3 (2015); 256-262
Eugenol is a compound with a variety of reactive functional groups such as allyl, hydroxy and methoxy. The presence of the functional groups brings eugenol possible to undertake the transformation into various derivative compounds with diverse activi...
Jurnal Institusi
Quantification of Andrographolide Isolated from Andrographis paniculata Nees Obtained from Traditional Market in Yogyakarta Using Validated HPLC
Indonesian Journal of Chemistry; Vol 16, No 2 (2016); 190-197
This research was aimed to quantification of andrographolide isolated from A. paniculata Ness found in traditional market in Yogyakarta using validated HPLC to obtain high level content of andrographolide. The extraction of andrographolide from A. pa...
Jurnal Institusi
QSAR Analysis of Benzothiazole Derivatives of Antimalarial Compounds Based On AM1 Semi-Empirical Method
Indonesian Journal of Chemistry; Vol 15, No 1 (2015); 86-92
Quantitative Structure and Activity Relationship (QSAR) analysis of 13 benzothiazoles derivatives compound as antimalarial compounds have been performed using electronic descriptor of the atomic net charges (q), dipole moment (μ), ELUMO, EHOMO and p...
Jurnal Institusi
Anionic and Cationic Dyes Removal from Aqueous Solutions by Adsorption onto Synthetic Mg/Al Hydrotalcite-Like Compound
Indonesian Journal of Chemistry; Vol 15, No 3 (2015); 234-241
The current investigation reports an effective adsorption of both anionic species and cationic dyes on Mg/Al hydrotalcite-like compounds (Mg/Al HTlc) synthetic from brine water, as novel, inexpensive available alternative to the commercial hydrotalci...
Jurnal Institusi
Computer-Aided Drug Repurposing: A Cyclooxygenase-2 Inhibitor Celecoxib as a Ligand for Estrogen Receptor Alpha
Indonesian Journal of Chemistry; Vol 15, No 3 (2015); 274-280
A cyclooxygenase-2 (COX-2) inhibitor celecoxib has been previously reported to have cytotoxic activities towards gastric, prostate, ovarian, colon and breast cancer cell lines. This article reports that the cytotoxic activities of celecoxib could be ...
PubMed
Green extraction of puromycin-based antibiotics from Streptomyces albofaciens (MS38) for sustainable biopharmaceutical applications
Front Chem
Background: Microbial secondary metabolites have shown promise as a source of novel antimicrobial agents. In this study, we aimed to isolate, characterize, and evaluate the antimicrobial activity of compound from a novel Streptomyces albofaciens stra...
PubMed
Pharmacokinetic parameters explain the therapeutic activity of antimicrobial agents in a silkworm infection model
Sci Rep
Poor pharmacokinetic parameters are a major reason for the lack of therapeutic activity of some drug candidates. Determining the pharmacokinetic parameters of drug candidates at an early stage of development requires an inexpensive animal model with ...
PubMed
Isolation, purification and characterization of novel antimicrobial compound 7-methoxy-2,2-dimethyl-4-octa-4′,6′-dienyl-2H-napthalene-1-one from Penicillium sp. and its cytotoxicity studies
AMB Express
Fungus isolated from soil has been evaluated for its antimicrobial activity which showed broad spectrum antimicrobial activity against all the pathogenic microorganisms used. Optimization was done by response surface methodology (RSM) to further opti...
PubMed
Purification and biological analysis of antimicrobial compound produced by an endophytic Streptomyces sp.
Sci Rep
Fungal phytopathogens and drug-resistant bacteria are two significant challenges in agriculture and public health, respectively. As a result, new sources of antimicrobial compounds are urgently needed. Taking into consideration these aspects, the pre...
PubMed
Naringin derivatives as glucosamine-6-phosphate synthase inhibitors based preservatives and their biological evaluation
Sci Rep
Glucosamine-6-Phosphate synthase enzyme has been targeted for development of better and safe preservative due to its role in microbial cell wall synthesis. In recent year’s demand of preservatives for the food, cosmetics and pharmaceuticals have in...
PubMed
Aesculin based glucosamine-6-phosphate synthase inhibitors as novel preservatives for food and pharmaceutical products: in-silico studies, antioxidant, antimicrobial and preservative efficacy evaluation
BMC Chem
BACKGROUND: Presently available chemical based synthetic preservative have emerged with various side effects, so the aspiration of natural and side effect free novel preservative has been greatly increased. As the natural preservative exhibit poor si...
PubMed
Study of the Soil Isolates for Antimicrobial Activity
Indian J Pharm Sci
During the process of screening for a potent antimicrobial compound, a new strain was isolated from the soil sample of Thalaikunda village in Ooty, Tamil Nadu. That organism was name as NK(2). It was found to be antagonistic to both bacterial and fun...
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