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DOAJ Open Access

Stimuli‐Responsive Crosslinked Chitosan/PVP/PEG Hydrogel Networks for Targeted Drug Delivery and Antimicrobial Performance

Analytical Science Advances, Vol 7, Iss 1, Pp n/a-n/a (2026) | ISSN: 2628-5452
Wiley-VCH, 2026DOI: 10.1002/ansa.70065
ABSTRACT In this study, a unique pH‐sensitive PEG/C/PVA hydrogel based on chitosan (C), polyvinyl propylene (PVP) and polyethylenglycol (PEG) crosslinked with tetraethyl orthosilicate (TEOS) was fabricated. This PEG/C/PVA hydrogel was designed to d...
Jurnal Institusi

Significance of Glucose Addition on Chitosan-Glycerophosphate Hydrogel Properties

Indonesian Journal of Chemistry; Vol 16, No 1 (2016); 65-71
Universitas Gadjah Mada, 2018DOI: 10.22146/ijc.21179http://creativecommons.org/licenses/by-nc-nd/4.0
Chitosan-glycerophosphate hydrogel can be used as dental scaffold due to its thermosensitivity, gelation performance at body temperature, suitable acidity for body condition, biocompatibility, and ability to provide good environment for cell prolifer...
Jurnal Institusi

Cadmium Adsorption on Chitosan/Chlorella Biomass Sorbent Prepared by Ionic-Imprinting Technique

Indonesian Journal of Chemistry; Vol 15, No 2 (2015); 163-171
Universitas Gadjah Mada, 2015DOI: 10.22146/ijc.21210http://creativecommons.org/licenses/by-nc-nd/4.0
Ionic-Imprinted Chitosan/Chlorella biomass sorbent (IICCb) has been synthesized for selective adsorption of Cd(II) adsorption. IICCb was prepared by coating Cd(II)-complexed-chitosan hydrogel on the biomass surface followed by cross-linking procedure...
Jurnal Institusi

Photocatalytic Decolorization Study of Methyl Orange by TiO2–Chitosan Nanocomposites

Indonesian Journal of Chemistry; Vol 14, No 3 (2014); 209-218
Universitas Gadjah Mada, 2014DOI: 10.22146/ijc.21230http://creativecommons.org/licenses/by-nc-nd/4.0
The photocatalytic decolorization of methyl orange (MO) by TiO2-chitosan nanocomposite has been studied. This study was started by synthesizing TiO2-chitosan nanocomposites using sol-gel method with various concentrations of Titanium(IV) isopropoxide...
Jurnal Institusi

Preparation of Citric Acid Crosslinked Chitosan/Poly(Vinyl Alcohol) Blend Membranes for Creatinine Transport

Indonesian Journal of Chemistry; Vol 16, No 2 (2016); 144-150
Universitas Gadjah Mada, 2018DOI: 10.22146/ijc.21157http://creativecommons.org/licenses/by-nc-nd/4.0
Preparation of membrane using crosslinking reaction between chitosan and citric acid showed that functional group modification increased the number of active carrier groups which lead to better transport capacity of the membrane. In addition, the sub...
Jurnal Institusi

Synthesis and Characterization of Chitosan- Alginate for Controlled Release of Isoniazid Drug

Indonesian Journal of Chemistry; Vol 15, No 1 (2015); 16-21
Universitas Gadjah Mada, 2015DOI: 10.22146/ijc.21218http://creativecommons.org/licenses/by-nc-nd/4.0
The aim of this research was to synthesize and characterize chitosan-calcium alginate as matrix isoniazid encapsulation to produce controlled release isoniazid drug. The microparticles were evaluated for surface morphology, functional groups, size pa...
Jurnal Institusi

Synthesis of Silver-Chitosan Nanocomposites Colloidal by Glucose as Reducing Agent

Indonesian Journal of Chemistry; Vol 15, No 1 (2015); 29-35
Universitas Gadjah Mada, 2015DOI: 10.22146/ijc.21220http://creativecommons.org/licenses/by-nc-nd/4.0
Silver-chitosan nanocomposites colloidal was successfully performed by chemical reduction method at room temperature using glucose as reducing agent, sodium hydroxide (NaOH) as accelerator reagent, silver nitrate (AgNO3) as metal precursor and chitos...
Jurnal Institusi

Synthesis and Characterization of Chitosan/Phosphotungstic Acid-Montmorillonite Modified by Silane for DMFC Membrane

Indonesian Journal of Chemistry; Vol 15, No 3 (2015); 218-225
Universitas Gadjah Mada, 2015DOI: 10.22146/ijc.21188http://creativecommons.org/licenses/by-nc-nd/4.0
Montmorillonite was functionalized by (3-glycidyloxypropyl) trimethoxy silane (GPTMS). Subsequently, chitosan (CS) membranes filled by GPTMS-modified montmorillonite particles were prepared and characterized by FTIR. The result of FTIR obtained the p...
Jurnal Institusi

Preparation and Pb(II) Adsorption Properties of Crosslinked Pectin-Carboxymethyl Chitosan Film

Indonesian Journal of Chemistry; Vol 15, No 3 (2015); 248-255
Universitas Gadjah Mada, 2015DOI: 10.22146/ijc.21192http://creativecommons.org/licenses/by-nc-nd/4.0
A modified pectin has been synthesized by reacting/combining -OH group among pectin and chitosan with BADGE (Bisphenol A diglycidyl ether) crosslinker agent. The structure and morphology of the new material were characterized by Fourier transform inf...
Jurnal Institusi

Adsorption of Ca(II), Mg(II), Zn(II), and Cd(II) on Chitosan Membrane Blended with Rice Hull Ash Silica and Polyethylene Glycol

Indonesian Journal of Chemistry; Vol 16, No 1 (2016); 45-52
Universitas Gadjah Mada, 2018DOI: 10.22146/ijc.21176http://creativecommons.org/licenses/by-nc-nd/4.0
In this research, chitosan based membrane blended with rice hull ash (RHA) silica and polyethylene glycol (PEG) has been applied as adsorbent of Ca(II), Mg(II), Zn(II) and Cd(II) in an aqueous solution. Membrane was synthesized by blending RHA silica...
Jurnal Institusi

Preservation of Natural Colorant Extract of Jalawe Fruit Peel (Terminalia bellirica) in Water-Based Solution

Indonesian Journal of Chemistry; Vol 16, No 3 (2016); 315-321
Universitas Gadjah Mada, 2018DOI: 10.22146/ijc.21148http://creativecommons.org/licenses/by-nc-nd/4.0
The general objective of this study is to preserve natural colorant extract of jalawe fruit peel in water-based solution during storing. The specific objectives in this research are finding suitable type and amount of antimicrobial compound to preven...
Jurnal Institusi

Synthesis and Characterization Superabsorbent Hydrogels of Partially Neutralized Acrylic Acid Prepared Using Gamma Irradiation; Swelling and Thermal Behavior

Indonesian Journal of Chemistry; Vol 15, No 3 (2015); 281-287
Universitas Gadjah Mada, 2015DOI: 10.22146/ijc.21197http://creativecommons.org/licenses/by-nc-nd/4.0
A series of superabsorbent hydrogels were synthesized from partially neutralized acrylic acid with varying degree of neutralization (0-1) using gamma radiation. The effects of degree neutralization of acrylic acid on swelling ratio were studied. DSC ...
PubMed

Design and evaluation of chitosan-amino acid thermosensitive hydrogel

Mar Life Sci Technol
Springer, 2021DOI: 10.1007/s42995-021-00116-9© Ocean University of China 2021
Chitosan/glycerophosphate thermosensitive hydrogel crosslinked physically was a potential drug delivery carrier; however, long gelation time limits its application. Here, chitosan-amino acid (AA) thermosensitive hydrogels were prepared from chitosan ...
PubMed

Development of Thermosensitive Hydrogels of Chitosan, Sodium and Magnesium Glycerophosphate for Bone Regeneration Applications

J Funct Biomater
Multidisciplinary Digital Publishing Institute (MDPI), 2015DOI: 10.3390/jfb6020192http://creativecommons.org/licenses/by/4.0/
Thermosensitive injectable hydrogels based on chitosan neutralized with sodium beta-glycerophosphate (Na-β-GP) have been studied as biomaterials for drug delivery and tissue regeneration. Magnesium (Mg) has been reported to stimulate adhesion and pr...
PubMed

A Human Umbilical Cord Mesenchymal Stem Cell-Conditioned Medium/Chitosan/Collagen/β-Glycerophosphate Thermosensitive Hydrogel Promotes Burn Injury Healing in Mice

Biomed Res Int
Wiley, 2019DOI: 10.1155/2019/5768285https://creativecommons.org/licenses/by/4.0/
We investigated the effects of a human umbilical cord mesenchymal stem cell-conditioned medium (MSC-CM)/chitosan/collagen/β-glycerophosphate (β-GP) thermosensitive hydrogel (MSC-CM/hydrogel) on mice with third-degree burns. MSC-CM was collected and...
PubMed

Influence of the Degree of Deacetylation of Chitosan and BMP-2 Concentration on Biocompatibility and Osteogenic Properties of BMP-2/PLA Granule-Loaded Chitosan/β-Glycerophosphate Hydrogels

Molecules
Multidisciplinary Digital Publishing Institute (MDPI), 2021DOI: 10.3390/molecules26020261http://creativecommons.org/licenses/by/4.0/
Compositions based on chitosan/β-glycerophosphate hydrogels with highly porous polylactide granules can be used to obtain moldable bone graft materials that have osteoinductive and osteoconductive properties. To eliminate the influence of such chara...
PubMed
PubMed

Thermosensitive Chitosan-β-Glycerophosphate Hydrogels as Targeted Drug Delivery Systems: An Overview on Preparation and Their Applications

Adv Pharmacol Pharm Sci
Wiley, 2021DOI: 10.1155/2021/6640893https://creativecommons.org/licenses/by/4.0/
Today, with the advances in technology and science, more advanced drug delivery formulations are required. One of these new systems is an intelligent hydrogel. These systems are affected by the environment or conditions that become a gel, stay in the...
PubMed

In Vitro Release of 5-Fluorouracil and Methotrexate from Different Thermosensitive Chitosan Hydrogel Systems

AAPS PharmSciTech
2020DOI: 10.1208/s12249-020-01672-6http://creativecommons.org/licenses/by/4.0/
5-Fluorouracil is a member of cytotoxic drugs with poor selectivity to cancer cells. Currently, systemic administration of this anti-cancer drug (oral or injection) exposes normal tissues to the drug-induced toxicity. Nowadays, attention has been gre...
PubMed