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PubMed

Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells

J Immunol
2009DOI: 10.4049/jimmunol.182.2.1119Copyright © 2009 by The American Association of Immunologists, Inc.
House dust mites are a significant source of airborne allergen worldwide, but there is little understanding of how they so potently generate allergic inflammation. We found that extracts from the house dust mites Dermatophagoides farinae (Df) and Der...
PubMed

Collagen VI regulates satellite cell self-renewal and muscle regeneration

Nat Commun
2013DOI: 10.1038/ncomms2964Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
Adult muscle stem cells, or satellite cells play essential roles in homeostasis and regeneration of skeletal muscles. Satellite cells are located within a niche that includes myofibers and extracellular matrix. The function of specific extracellular ...
PubMed

ROC Analysis in Biomarker Combination with Covariate Adjustment

Acad Radiol
RATIONAL AND OBJECTIVES: Receiver operating characteristic analysis (ROC) is often used to find the optimal combination of biomarkers. When the subject level covariates affect the magnitude and/or accuracy of the biomarkers, the combination rule shou...
PubMed

Photo-Fries-based photosensitive polymeric interlayers for patterned organic devices

Appl Phys A Mater Sci Process
2012DOI: 10.1007/s00339-012-6853-2https://creativecommons.org/licenses/by/4.0/
This work reports on the investigation of the photosensitive polymer poly(diphenyl bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate) (PPNB), which undergoes the photo-Fries rearrangement upon illumination with UV-light, used as interfacial layers in organi...
PubMed

New approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania

Neuropsychiatr Dis Treat
Dove Press, 2013DOI: 10.2147/NDT.S16078© 2013 Warren and Dubovsky, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
Bipolar disorder is a prevalent disorder that tends to become progressive without treatment and with inadequate treatment. Second generation (atypical) antipsychotic drugs have increasingly been used as adjunctive treatment or monotherapy for mania, ...
PubMed

The cost of schizophrenia in Japan

Neuropsychiatr Dis Treat
Dove Press, 2013DOI: 10.2147/NDT.S41632© 2013 Sado et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
INTRODUCTION: Schizophrenia is a disorder that produces considerable burdens due to its often relapsing/remitting or chronic longitudinal course. This burden is felt not only by patients themselves, but also by their families and health care systems....
PubMed

Effects of pentoxifylline, 7-nitroindazole, and imipramine on tumor necrosis factor-α and indoleamine 2,3-dioxygenase enzyme activity in the hippocampus and frontal cortex of chronic mild-stress-exposed rats

Neuropsychiatr Dis Treat
Dove Press, 2013DOI: 10.2147/NDT.S41020© 2013 Mohamed et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
OBJECTIVES: This study aimed to investigate the role of tumor necrosis factor (TNF)-α and the neuronal nitric oxide synthase enzyme in dysregulation of indoleamine 2,3-dioxygenase (IDO) enzyme, and hence serotonin availability in chronic mild stress...
PubMed

Treatment in hospital for alcohol-dependent patients decreases attentional bias

Neuropsychiatr Dis Treat
Dove Press, 2013DOI: 10.2147/NDT.S42556© 2013 Flaudias et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
BACKGROUND AND OBJECTIVES: Previous studies in alcohol-dependent patients have shown an attentional bias (AB) under related substance cues, which can lead to relapse. This AB can be evaluated by the alcohol Stroop test (AST). The AST is a modified St...
PubMed

A Church-Based Diet and Physical Activity Intervention for Rural, Lower Mississippi Delta African American Adults: Delta Body and Soul Effectiveness Study, 2010–2011

Prev Chronic Dis
Centers for Disease Control and Prevention, 2013DOI: 10.5888/pcd10.120286https://creativecommons.org/licenses/by/4.0/
INTRODUCTION: Obesity, diabetes, and hypertension have reached epidemic levels in the largely rural Lower Mississippi Delta (LMD) region. We assessed the effectiveness of a 6-month, church-based diet and physical activity intervention, conducted duri...
PubMed

Using Geographic Information Systems to Compare Municipal, County, and Commercial Parks Data

Prev Chronic Dis
Centers for Disease Control and Prevention, 2013DOI: 10.5888/pcd10.120265https://creativecommons.org/licenses/by/4.0/
INTRODUCTION: Parks are an integral part of a favorable built environment, and several studies have found a positive association between a favorable built environment and physical activity. Parks data are available to researchers from various sources...
PubMed

Plasma Vitamin D and Biomarkers of Cardiometabolic Disease Risk in Adult Canadians, 2007–2009

Prev Chronic Dis
Centers for Disease Control and Prevention, 2013DOI: 10.5888/pcd10.120230https://creativecommons.org/licenses/by/4.0/
INTRODUCTION: Vitamin D may modulate cardiometabolic disease risk, although the relationship has not been investigated in the general Canadian population. Understanding this relationship may inform public health strategies to curb the incidence of ca...
PubMed

No Financial Disincentive for Choosing More Healthful Entrées on Children’s Menus in Full-Service Restaurants

Prev Chronic Dis
Centers for Disease Control and Prevention, 2013DOI: 10.5888/pcd10.120266https://creativecommons.org/licenses/by/4.0/
Children are eating restaurant foods more than ever before, and price is among the top considerations for food choices. We categorized and enumerated entrées on children’s menus from 75 full-service restaurant chains to compare prices of more heal...
PubMed

Dams and Disease Triggers on the Lower Mekong River

PLoS Negl Trop Dis
PLOS, 2013DOI: 10.1371/journal.pntd.0002166https://creativecommons.org/licenses/by/4.0/
PubMed

Molecularly targeted approaches herald a new era of non-small-cell lung cancer treatment

Cancer Manag Res
Dove Press, 2013DOI: 10.2147/CMAR.S32973© 2013 Kaneda et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
The discovery of activating mutations in the epidermal growth-factor receptor (EGFR) gene in 2004 opened a new era of personalized treatment for non-small-cell lung cancer (NSCLC). EGFR mutations are associated with a high sensitivity to EGFR tyrosin...
PubMed

Inhaled anticholinergic use and all-cause mortality among elderly Medicare beneficiaries with chronic obstructive pulmonary disease

Int J Chron Obstruct Pulmon Dis
Dove Press, 2013DOI: 10.2147/COPD.S45166© 2013 Ajmera et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
BACKGROUND: The purpose of this study was to examine the association between use of inhaled anticholinergics and all-cause mortality among elderly individuals with chronic obstructive pulmonary disease (COPD), after controlling for demographic, socio...
PubMed

Prognostic factors of tumor recurrence in completely resected non-small cell lung cancer

Cancer Manag Res
Dove Press, 2013DOI: 10.2147/CMAR.S45642© 2013 Tantraworasin et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
BACKGROUND: Patients with completely resected non-small cell lung cancer (NSCLC) have an excellent outcome; however tumor recurs in 30%–77% of patients. This study retrospectively analyzed the clinicopathologic features of patients with any operabl...
PubMed

Factors that Affect Integrity of Authorship of Scientific Meeting Abstracts

AJOB Prim Res
BACKGROUND: Strict criteria for manuscript authorship exist to guide decisions on who should be considered an author. Less is known about how authorship for scientific meetings is determined. Our goal was to explore factors that influence decisions a...
PubMed

The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation

Science
Eukaryotic cells can use the autophagy pathway to defend against microbes that gain access to the cytosol or reside in pathogen-modified vacuoles. It remains unclear if pathogens have evolved specific mechanisms to manipulate autophagy. Here we find ...
PubMed

Attitudes and beliefs about anti-retroviral therapy are associated with high risk sexual behaviors among the general population of Kisumu, Kenya

AIDS Care
2011DOI: 10.1080/09540121.2011.579947© 2011 Taylor & Francis
Attitudes and beliefs about antiretroviral therapy (ART) may affect sexual risk behaviors among the general population in sub-Saharan Africa. We performed a cross-sectional population-based study in Kisumu, Kenya to test this hypothesis in October 20...
PubMed

Solutions for Determining the Significance Region Using the Johnson-Neyman Type Procedure in Generalized Linear (Mixed) Models

J Educ Behav Stat
Researchers often compare the relationship between an outcome and covariate for two or more groups by evaluating whether the fitted regression curves differ significantly. When they do, researchers need to determine the “significance region,” or ...